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1

Specific stabilization of DNA triple helices by indolo[2,1-b]quinazolin-6,12-dione derivatives

Grace Shiahuy Chen, Bhalchandra V. Bhagwat, Pei-Yin Liao, Hui-Ting Chen, Shwu-Bin Lin, Ji-Wang Chern

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 349 KB

english, 2007

2

Microwave-Assisted Cross-Coupling for the Construction of Diaryl Sulfides

Chen-Ming Tan, Grace Shiahuy Chen, Chien-Shu Chen, Ji-Wang Chern

Journal:

Journal of the Chinese Chemical Society

Year:

2011

Language:

english

File:

PDF, 487 KB

english, 2011

3

Reactions of anthranilamide with isocyanates: A new facile synthesis of 2,3-dihydro-5H-oxazolo[2,3-b]quinazolin-5-one and 3,4-dihydro-2H,6H-[1,3]oxazino[2,3-b]quinazolin-6-one [1]

Ji-Wang Chern, Fang-Jy Shish, Chau-Dung Chang, Chao-Han Chan, Kang-Chien Liu

Journal:

Journal of Heterocyclic Chemistry

Year:

1988

File:

PDF, 207 KB

1988

4

Reactions of 2-aminothiobenzamide with isocyanates: A new synthesis of 2, 3-dihydroimidazo[1, 2-c]quinazolin-5(6H)-one and 3, 4-Dihydro-2H-pyrimido[1, 2-c]quinazolin-6(7H)-one

Chia-Yang Shiau, Ji-Wang Chern, Jung-Hsiung Tien, Kang-Chien Liu

Journal:

Journal of Heterocyclic Chemistry

Year:

1989

File:

PDF, 158 KB

1989

5

Quinazolin-4-one Derivatives as Selective Histone Deacetylase-6 Inhibitors for the Treatment of Alzheimer’s Disease

Yu, Chao-Wu, Chang, Pei-Teh, Hsin, Ling-Wei, Chern, Ji-Wang

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 884 KB

english, 2013

6

4-Substituted 2-amino-3,4-dihydroquinazolines with a 3-hairpin turn side chain as novel inhibitors of BACE-1

Dhananjay Jagtap, Ajit, Kondekar, Nagendra B., Hung, Pei-Yun, Hsieh, Chen-En, Yang, Chia-Ron, Shiahuy Chen, Grace, Chern, Ji-Wang

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 1.11 MB

english, 2019

7

Cure of malignant ascites and generation of protective immunity by monoclonal antibody–targeted activation of a glucuronide prodrug in rats

Bing-Mae Chen, Lai-Yee Chan, Shing-Ming Wang, Ming-Fang Wu, Ji-Wang Chern, Steve R. Roffler

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 433 KB

english, 1997

8

Synthese und anorektische Wirkung einiger kondensierter Perimidin-Derivate

Kang-Chien Liu, Hsiu-Ho Chen, Liang-Chu Lee, Ji-Wang Chern

Journal:

Archiv der Pharmazie

Year:

1979

File:

PDF, 236 KB

1979

9

Synthese und antihypertensive Aktivität von 2-Methyl-5,6-dihydro-4(H)-oxo-1,3-thiazino[2,3-b]chinazolin

Kang-Chien Liu, Mou-Hsiung Yen, Ji-Wang Chern, Yueh-O Lin

Journal:

Archiv der Pharmazie

Year:

1983

Language:

german

File:

PDF, 181 KB

german, 1983

10

Synthese und antihypertensive Aktivität einiger 2,3-Dihydro-5H-thiazolo[2,3-b]chinazolin-Derivate Synthesis and Antihypertensive Activities of Some 2,3-Dihydro-5H-thiazolo[2,3-b]quinazoline Derivatives

Kang-Chien Liu, Ji-Wang Chern, Mou-Hsiung Yen, Yueh-O Lin

Journal:

Archiv der Pharmazie

Year:

1983

File:

PDF, 165 KB

1983

11

ChemInform Abstract: A New Route Towards the Synthesis of Substituted Naphthalenes via Friedel—Crafts Acylation.

Chai-Lin Kao, Shu Y. Yen, Ji-Wang Chern

Journal:

Year:

2000

File:

PDF, 28 KB

2000

12

ChemInform Abstract: A Convenient Synthesis of Naturally Occurring Benzofuran Ailanthoidol.

Chai-Lin Kao, Ji-Wang Chern

Journal:

Year:

2001

File:

PDF, 31 KB

2001

13

Nucleosides. Part 9. Synthesis of Purine N3,5′-Cyclonucleosides and N3,5′-Cyclo-2′,3′-seconucleosides via Mitsunobu Reaction as TIBO-Like Derivatives.

Grace Shiahuy Chen, Chien-Shu Chen, Tun-Cheng Chien, Jun-Yen Yeh, Chia-Chi Kuo, Rahul Subhash Talekar, Ji-Wang Chern

Journal:

Year:

2004

File:

PDF, 127 KB

2004

14

Nucleosides. Part 11. Synthesis and Antiviral Evaluation of 5′-Alkylthio-5′-deoxy Quinazolinone Nucleoside Derivatives as S-Adenosyl-L-homocysteine Analogues.

Tun-Cheng Chien, Chien-Shu Chen, Fang-Hwa Yu, Ji-Wang Chern

Journal:

Year:

2005

File:

PDF, 30 KB

2005

15

ChemInform Abstract: Efficient Microwave-Assisted Synthesis of Ellipticine Through N-(1,4-Dimethyl-9H-carbazol-3-ylmethyl)-N-tosylaminoacetaldehyde Diethyl Acetal.

Hsueh-Yun Lee, Grace Shiahuy Chen, Chien-Shu Chen, Ji-Wang Chern

Journal:

Year:

2010

File:

PDF, 22 KB

2010

16

Synthesis of Anti-Microtubule N-(2-Arylindol-7-yl)benzenesulfonamide Derivatives and Their Antitumor Mechanisms

Chun-Tang Chiou, Grace Shiahuy Chen, Meng-Ling Chen, Huoming Li, Lei Shi, Xiang-Hong Huang, Wei-Ming Dai, Ji-Wang Chern

Journal:

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

17

Efficient microwave-assisted synthesis of ellipticine through N-(1,4-dimethyl-9H-carbazol-3-ylmethyl)-N- tosylaminoacetaldehyde diethyl acetal

Hsueh-Yun Lee, Grace Shiahuy Chen, Chien-Shu Chen, Ji-Wang Chern

Journal:

Journal of Heterocyclic Chemistry

Year:

2010

Language:

english

File:

PDF, 130 KB

english, 2010

18

1,2,4 Benzothiadiazine 1,1-dioxide. V: 1 synthesis of built-in hydroxuguanidine tricycles as potential anticancer agents

Ji-Wang Chern, Jiann-Gwo Rong

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 237 KB

english, 1991

19

Studies on quinazolines. 6. Asymmetric synthesis of (S)-(+)- and (R)-(−)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylthio-2,3-dihydroimidazo[1,2-c]quinazolines

Gutcait Alexander, Wang Kuang-Chao, Liu Hsiu-Wen, Chern Ji-Wang

Journal:

Tetrahedron: Asymmetry

Year:

1996

Language:

english

File:

PDF, 480 KB

english, 1996

20

Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase

Xin Cao, Qi-Dong You, Zhi-Yu Li, Qing-Long Guo, Jing Shang, Ming Yan, Ji-Wang Chern, Men-Ling Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

21

The design, synthesis and biological evaluation of 7-alkoxy-4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS

Xin Cao, Qi-Dong You, Zhi-Yu Li, Xiao-Rong Liu, Dan Xu, Qing-Long Guo, Jing Shang, Ji-Wang Chern, Meng-Ling Chen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

22

A convenient preparation of 1,2,3-tri-O-acetyl-β-d-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

Tun-Cheng Chien, Ji-Wang Chern

Journal:

Carbohydrate Research

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

23

The β-Carboline Analog Mana-Hox Causes Mitotic Aberration by Interacting with DNA

Lan Chun Tu, Chien-Shu Chen, I-Ching Hsiao, Ji-Wang Chern, Chi-Hung Lin, Ya-Ching Shen, Sheau Farn Yeh

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 987 KB

english, 2005

24

A new route towards the synthesis of substituted naphthalenes via Friedel–Crafts acylation

Chai-Lin Kao, Shu Y Yen, Ji-Wang Chern

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

25

A convenient synthesis of naturally occurring benzofuran ailanthoidol

Chai-Lin Kao, Ji-Wang Chern

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

26

A novel and efficient synthesis of isoguanosine

Chern Ji-Wang, Lee Horng-Yuh, Huang Min, Shish Fang-Jy

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 221 KB

english, 1987

27

A novel and efficient synthesis of the naturally occurring nucleoside doridosine

Ji-Wang Chern, Leroy B. Townsend

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 264 KB

english, 1985

28

Studies on quinazolinones. 3: 1 novel and efficient route to the synthesis of conformationally restricted analogues of ketanserin and SGB-1534 as antihypertensive agents

Ji-Wang Chern, Chia-Yang Shiau, Guan-Yu Lu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 274 KB

english, 1991

29

Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: the roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathways

Chiung-Hua Huang, Jih-Hwa Guh, Grace Shiahuy Chen, Pin-Hsuan Lu, Ji-Wang Chern

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2010

Language:

english

File:

PDF, 659 KB

english, 2010

30

Poly(ethylene glycol) modification of β-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs

Tian-Lu Cheng, Bing-Mae Chen, Lai-Yee Chan, P.-Y. Wu, Ji-Wang Chern, S. R. Roffler

Journal:

Cancer Immunology, Immunotherapy

Year:

1997

Language:

english

File:

PDF, 270 KB

english, 1997

31

Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-α production

Chien-Shu Chen, Chen-Ming Tan, Chiung-Hua Huang, Ling-Chu Chang, Jih-Pyang Wang, Fong-Chi Cheng, Ji-Wang Chern

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

32

Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes

Yi-Pei Lin, Feng-Lin Hsu, Chien-Shu Chen, Ji-Wang Chern, Mei-Hsien Lee

Journal:

Year:

2007

Language:

english

File:

PDF, 926 KB

english, 2007

33

Corrigendum to “Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes” [Phytochemistry 68 (2007) 1189–1199]

Yi-Pei Lin, Feng-Lin Hsu, Chien-Shu Chen, Ji-Wang Chern, Mei-Hsien Lee

Journal:

Year:

2007

File:

PDF, 65 KB

2007

34

Studies on quinazolines IX:1 Fluorination versus 1,2-migration in the reaction of 1,3-bifunctionalized amino-2-propanol with DAST

Ji-Wang Chern, Jun-Yi Chang, Cyril O. Usifoh, Alexander Gutsait

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

35

Portal hypertensive effects of combined terlipressin and DL-028, a synthetic α1 adrenoceptor antagonist administration on anesthetized portal hypertensive rats

Yi-Tsau Huang, Li-Chih Lin, Ji-Wang Chern, Han-Chieh Lin, Chuang-Ye Hong

Journal:

Liver International

Year:

1999

Language:

english

File:

PDF, 650 KB

english, 1999

36

A Convenient Synthesis of 2-N-Methoxycarbonylaminooxazolo[5,4-d]pyrimidines

Ji-Wang Chern, Dean S. Wise, Leroy B. Townsend

Journal:

Journal of Heterocyclic Chemistry

Year:

1984

File:

PDF, 133 KB

1984

37

An unexpected product from the cyclodesulfurization of 5-[1-(3-methoxycarbonyl)thioureido]-1-(β-D-ribofuranosyl)imidazole-4- carboxamide with dicyclohexylcarbodiimide

Ji-Wang Chern, Michael P. Groziak, Leroy B. Townsend

Journal:

Journal of Heterocyclic Chemistry

Year:

1986

Language:

english

File:

PDF, 155 KB

english, 1986

38

Condensed 1,3-benzothiazinones. 1. Facile synthesis of 2-amino-1,2,4-triazolo[5,1-b][1,3]-benzothiazin-9-one

Kang-Chien Liu, Bi-Jane Shih, Ji-Wang Chern

Journal:

Journal of Heterocyclic Chemistry

Year:

1988

File:

PDF, 184 KB

1988

39

Condensed 1,3-benzothiazinones. 2. Synthesis of 2-substituted 1,2,4-triazolo[5,1-b][1,3]benzothiazin-9-ones

Kang-Chien Liu, Bi-Jane Shih, Ji-Wang Chern

Journal:

Journal of Heterocyclic Chemistry

Year:

1989

File:

PDF, 345 KB

1989

40

Condensed 1,3-benzothiazinones 3. Synthesis of 3-substituted 1,2,4-triazolo[3,4-b][1,3]benzothiazin-5-ones

Kang-Chien Liu, Bi-Jane Shih, Ji-Wang Chern

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 424 KB

1990

41

Studies on quinazolinones. 2. Synthesis of 2-(4-benzylpiperazin-1-ylmethyl)-2,3-dihydro-5H-oxazolo[2,3–6]quinazolin-5-one and -2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one

Chia-Yang Shiau, Ji-Wang Chern, Kang-Chien Liu, Chao-Han Chan, Mou-Hsiung Yen, Ming-Chu Cheng, Yu Wang

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 460 KB

1990

42

2H-1,2,4-benzothiadiazine 1,1-dioxides 2. A condensation of 2-aminobenzenesulfonamide with chloroalkyl isothiocyanates

Ji-Wang Chern, Ying-Hwa Wu, Kang-Chien Liu

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 274 KB

1990

43

1,2,4-benzothiadiazine 1,1-dioxides 3. Reactions of 2-aminobenzenesulfonamide with chloroalkyl isocyanates

Ji-Wang Chern, Ching-Po Ho, Ying-Hwa Wu, Jiann-Gwo Rong, Kang-Chien Liu, Ming-Chu Cheng, Yu Wang

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 508 KB

1990

44

Antihypertensive and hypolipidemic effects of DC-015, a novel, potent and specific α1-adrenoceptor antagonist: Comparison with prazosin in spontaneously hypertensive rats

I-Hsun Peng, Joen-Rong Sheu, Ji-Wang Chern, Yen-Mei Lee, Mao-Hsiung Yen

Journal:

Journal of Biomedical Science

Year:

1996

Language:

english

File:

PDF, 1.18 MB

english, 1996

45

Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors

Chen-Ming Tan, Grace Shiahuy Chen, Chien-Shu Chen, Pei-Teh Chang, Ji-Wang Chern

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 740 KB

english, 2011

46

Investigation of anticancer mechanism of thiadiazole-based compound in human non-small cell lung cancer A549 cells

Jui-Yi Chou, Shin-Yu Lai, Shiow-Lin Pan, Guey-Mei Jow, Ji-Wang Chern, Jih-Hwa Guh

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 337 KB

english, 2003

47

Characterization of an antineoplastic glucuronide prodrug

Tian-Lu Cheng, Wan-Chih Chou, Bing Mae Chen, Ji-Wang Chern, Steve R Roffler

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 327 KB

english, 1999

48

Characterization of some novel α1-adrenoceptor antagonists in human hyperplastic prostate

Shih-Chieh Chueh, Ji-Wang Chern, Chee-Min Choong, Jih-Hwa Guh, Che-Ming Teng

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

49

Pharmacological characterization of EK112, a new combined angiotensin II and thromboxane A2 receptor antagonist

Tsong-Long Hwang, Yung-An Yeh, Ji-Wang Chern, Che-Ming Teng

Journal:

General Pharmacology: The Vascular System

Year:

2000

Language:

english

File:

PDF, 220 KB

english, 2000

50

Anti-neoplastic glucuronide prodrug treatment of human tumor cells targeted with a monoclonal antibody-enzyme conjugate

Steven R. Roffler, Shing-Ming Wang, Ji-Wang Chern, Ming-Yang Yeh, Edward Tung

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 408 KB

english, 1991